Ljungan virus (LV) is a picornavirus originally isolated from Swedish bank voles ( Myodes glareolus ) in 1998. The association of LV with human disease has been debated ever since, but fundamental

2015-10-08 · Ljungan virus (LV), a picornavirus originally isolated from voles, has been proposed as a zoonotic virus, potentially associated with type-1 diabetes mellitus, myocarditis and Guillain–Barré

2013).In northern Italy, this virus has been reported in a small sample of bank voles (Myodes glareolus) and yellow-necked mice (Apodemus flavicollis) with 50% and 10% Ljungan virus (LV), a picornavirus, was discovered in the Swedish vole population after six clustered deaths from myocarditis were noted in orienteers between 1989 and 1992. Four of five sera from the orienteer patients had detectable antibodies against one of the LV isolates. Wild bank voles (Myodes glareolus) develop T1D and a picornavirus, named Ljungan virus (LV), has been isolated from these animals. If CD-1 mice, that normally do not carry LV, are infected with this virus in utero and exposed to stress after birth, the male offspring get type 2 diabetes. Bank voles (Clethrionomys glareolus) kept in captivity develop diabetes mellitus to a significant extent. Also in wild bank voles, elevated blood glucose has been observed.

1999), and has subsequently been detected in many species of small rodents, especially voles (Arvicolinae; Johansson et al. 2003; Hauffe et al. 2010; Salisbury et al. 2013).

Ljungan virus types 1 to 6 belong to the species Parechovirus B, genus Parechovirus.. The partial genome sequence of a virus isolated from bank voles (Clethrionomys glareolus) was originally determined by Niklasson et al.

In BB rats LV was found in both prediabetic- and diabetic DPBB rats, as well as in diabetes-resistant rats. To The Ljungan virus is difficult to grow in a laboratory cell cultures. This method is therefore rarely successful for diagnosing Ljungan virus infection. - The Ljungan virus’ so called “2A gene” is doubled, which means that its gene pool is organised in a way that separates it from most other known picorna viruses.

Ljungan virus (LV), which belongs to the Parechovirus genus in the Picornaviridae family, was first isolated from bank voles (Myodes glareolus) in Sweden in 1998 and proposed as a zoonotic agent.

Molecular characterization of a novel Ljungan virus (Parechovirus; Picornaviridae) reveals a fourth genotype and indicates ancestral recombination. J Gen Virol. 90: 843-653.

Ljungan Virus and an Adenovirus in Italian Squirrel Populations ClaudiaRomeo,1,6 NicolaFerrari, 2ChiaraRossi,3 DavidJ.Everest,4 SylviaS.Grierson,4 PaoloLanfranchi, Adriano Martinoli,5 Nicola Saino,1 Lucas A. Wauters,5 and Heidi C. Hauffe31Department of Biosciences, Universita` degli Studi di Milano, v. US20110300149A1 - Ljungan virus - Google Patents Ljungan virus Download PDF Info Publication number US20110300149A1. US20110300149A1 US13/141,758 US200913141758A US2011300149A1 US 20110300149 A1 US20110300149 A1 US 20110300149A1 US 200913141758 A US200913141758 A US 200913141758A US 2011300149 A1 US2011300149 A1 US 2011300149A1 The virus is a suspected human pathogen. Evidence: Literature Reference: PMID: 12163611: Authors: Johansson S, Niklasson B, Maizel J, Gorbalenya AE, Lindberg AM Title: Molecular analysis of three Ljungan virus isolates reveals a new, close-to-root lineage of the Picornaviridae with a cluster of two unrelated 2A proteins. Journal Three strains of Ljungan virus (LV) were isolated from bank voles (Clethrionomys glareolus) and A-2 plaque virus (A-2) was isolated from human sera. To study the genetic relationship between these recently discovered viruses and the members of the family Picornaviridae , an evolutionary analysis has been carried out using the amino acid sequences of the two nonstructural proteins 2C and 3D.
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Let's look at some of the features that make this disease so unusual. HIV can be transmitted through a variety of body fluids from infected individuals, Herpes is a virus that can cause sores on the skin. There are 2 types of the virus. FAQs Ask a Question Toll Free Numbers Media Contact Hospitals and Clinics Vet Centers Regional Benefits Offices Regional Loan Centers Cemetery Locations Her Johns Hopkins Medicine Podcasts All Podcasts, Health Newsfeed, Infectious diseases October 19, 2020 Podcast: Download (Duration: 1:05 — 1.5MB) Subscribe: Android | RSS Anchor lead: Volunteers in the UK plan to allow themselves to be infecte 8 Feb 2010 OBJECTIVE Ljungan virus (LjV) has been proposed as a potential environmental factor for type 1 diabetes. The objective was to test for any Keywords: Picornavirus Ljungan virus Sebokele virus Parechovirus Bird Ljungan and Sebokele viruses are two members of the genus Parechovirus within the 20 May 2020 hippocampus region of 18 AD cases and 11 age-matched controls using a polyclonal antibody against Ljungan virus (LV) capsid protein 1.

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Under dessa år var han också med och upptäckte ett nytt virus hos sorkar vid älven Ljungan i Härjedalen. Han gav det namnet Ljunganviruset

Cover image for Geographical Distribution of Ljungan Virus in Small Mammals in Europe. Scientific publication av B Andersson — Nyligen har ett nytt virus isolerats från sork infångad vid floden Ljungan i Medelpad varför virus benämns Ljunganvirus. Detta virus tillhör liksom enterovirus Sammanfattning: Ljungan virus (LV) is a recently identified picornavirus of the genus Parechovirus. LV has been isolated from voles trapped in Sweden and also [Irrelevant about Ljungan. virus] · Tomas Bergström, Jan-Åke Liljeqvist Läkartidningen - 2009-01-01. Characterization of polyclonal antibodies against the capsid Parechovirus B (Ljungan virus).